Pathogenic Mechanisms
The great majority of tubulointerstitial disorders occur as a result of one of three general mechanisms: heredity, toxic injury, or a change in tubule regulation by drugs or hormones. Polycystic kidney disease, familial nephrogenic diabetes insipidus, and Fanconi’s syndrome are disorders of hereditary origin. The specific genetic defects are unknown. Analgesic nephropathy, lead nephropathy, and some types of renal tubular acidosis are representative of toxic injuries. Pituitary diabetes insipidus (ADH deficiency), adrenal salt wasting (deficient mineralocorticoid), and diuretic administration are examples of the last category .
- Polycystic Kidney Disease (PKD)
- Management
- COMPLICATIONS OF MYOCARDIAL INFARCTION AND THEIR MANAGEMENT
- Clinical Manifestations
- Genitourinary System
- Phenytoin
- POSTCAPILLARY PULMONARY HYPERTENSION
- Verapamil
- OXYGEN THERAPY AND MECHANICAL VENTILATION
- TREATMENT OF MALABSORPTION
- Renal Artery Stenosis
- Endoscopic “Retrograde” Cholangiopancreatography (ERCP)
- Hypersensitivity Pneumonitis
- CLINICAL FEATURES OF PULMONARY HYPERTENSION
- ADAPTATION TO NEPHRON LOSS
- Comprehensive Health-care Program for Children in Foster Care
- CHROMC BROriCMITIS
- Sickle Cell Anemia (SS)
- DIFFUSE LUNG DISEASE OF UNKNOWN ETIOLOGY
- THE COMMON CLINICAL MANIFESTATIONS OF GASTROINTESTINAL DISEASE
- Amiodarone
- CLINICAL MANIFESTATIONS
- APPROACH TO THE PATIENT WJTH SUSPECTED MALDIGESTION AND/OR MALABSORPTION
- PROGNOSIS
- INVASIVE DIAGNOSTIC TECHNIQUES
- V-GASTROINTESTINAL DISEASE
- PENETRATING TRAUMA
- ATRIAL RHYTHM DISTURBANCES
- Endocrine Systems
- SCREENING TESTS OF HEPATOBILIARY DISEASE
- OXYGEN
- Progressive Crescentic Glomerulonephritis
- ENVIRONMENTAL DAMAGE OF THE EXTREMITIES
- Renal Venous Occlusion
- Pulmonary System