Pulmonary Vasculitis
Pulmonary vasculitis may occur as a part of one of the aforementioned connective tissue disorders or in the course of a systemic granulomatous or hypersensitivity vasculitis.
The granulomatous vasculitides include classic Wegener’s granulomatosis, limited Wegener’s, and lymphomatoid granulomatosis. Classic Wegener’s is a necrotizing vasculitis initially described as involving three organ systems: the lung, the upper respiratory tract, and the kidneys. However, many other organs in the body may be affected. Lung involvement usually takes the form of single or multiple nodular lesions that have a propensity to cavitate. The limited form of Wegener’s granulomatosis refers to patients with similar pathology but free of renal disease. Both diseases respond well to cyclophosphamide. Lymphomatoid granulomatosis resembles Wegener’s but differs in three important features: there is frequent central nervous system involvement, more than 15 per cent develop malignant lymphoma, and although cyclophosphamide may achieve remission, relapses are very common.
In hypersensitivity vasculitis, pulmonary involvement is a less prominent part of a systemic disease. The disorders in which this is most commonly seen are anaphylactoid purpura, essential mixed cryoglobulinemia, and the vasculitis associated with malignancy, infection, or drugs.
- EFFECTS OF PULMONARY HYPERTENSION ON PULMONARY FUNCTION
- PHYSIOLOGICAL EFFECTS OF PULMONARY HYPERTENSION ON CARDIAC FUNCTION
- Other Clearly Extrinsic Causes of Diffuse Infiltrative Lung Disease
- CLINICAL FEATURES OF PULMONARY HYPERTENSION
- GROSS ANATOMY
- Outcomes of Dialysis
- Alterations in Glomerular Hemodynamics, Parathyroid Hormone Metabolism, and Systemic Arterial Blood Pressure
- Systemic Lupus Erythematosus (SLE)
- Cardiovascular
- Community Acquired Pneumonia
- NAUSEA AND VOMITING
- Pyuria
- BILIRUBIN METABOLISM
- Bretylium Tosylate
- Renal Tubular Acidosis
- GLOMERULAR DISEASE
- CAUSES OF PULMONARY HYPERTENSION
- NORMAL GASTRIC PHYSIOLOGY
- Factors Involved in the Choice of Type of Dialysis
- Neurologic Manifestations
- PERIPHERAL VENOUS DISEASE
- FACTORS AFFECTING THE RATE OF LOSS OF NEPHRONS
- CARDIAC TUMORS
- THE ZOLLINGER-ELLISON SYNDROME
- CHEST WALL DISEASE
- SPECIFIC PATHOGENIC ORGANISMS
- MOXIOUS GASES AflD FUMES
- Genitourinary System
- Multiple Myeloma
- EFFECTORS OF THE RESPIRATORY SYSTEM
- SPECIFIC CLINICAL DISORDERS
- SPECIFIC MANIFESTATIONS OF RENAL DISEASE
- ARRHYTHMIAS in ACUTE MYOCARDIAL MFARCTION
- CARDIAC TRAUMA
- DRUGS