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Skin and Conjunctiva



Itching and conjunctivitis are common mani­festations of end-stage renal disease.- and appear to represent the clinical sequelae of microcrys-tallization of calcium. In addition, PTH itself may cause pruritus. As a consequence of poor nutrition and the defects in platelet function, poor skin tex­ture and bruising are common. In long-standing ESRD patients, there is darkening of the skin, per­haps related to retention of substances that stim­ulate melanin production.




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